PROTEOMICS IN NON-HUMAN PRIMATES: UTILIZING RNA-SEQ DATA TO IMPROVE PROTEIN IDENTIFICATION BY MASS SPECTROMETRY IN VERVET MONKEYS

Proteomics in non-human primates: utilizing RNA-Seq data to improve protein identification by mass spectrometry in vervet monkeys

Abstract Background Shotgun proteomics utilizes a database search strategy to compare detected mass spectra to a library of theoretical spectra derived from reference genome information.As such, the robustness of proteomics results is contingent upon the completeness and accuracy of the gene annotation in the reference genome.For animal models of d

read more




Dynamics of Activation and Regulation of the Immune Response to Attack by Viral Pathogens Using Mathematical Modeling

Blankets In this paper, a mathematical model is developed to simulate the activation of regulatory T lymphocytes dynamics.The model considers the adaptive immune response and consists of epithelial cells, infected cells, free virus particles, helper and cytotoxic T lymphocytes, B lymphocytes, and regulatory T lymphocytes.A mathematical analysis was

read more